What is Tadalafil?

Tadalafil is a brand name for a substance with the chemical name tadalafil

It is used to treat men who experience difficulty having and maintaining an erection to orgasm.

It was first introduced in February 2003 and it was approved by the FDA on November 21, 2003. Tadalafil was first marketed by Lilly ICOS, a joint venture between Eli Lilly and ICOS Corporation.

The standard starting dose size is 10 milligrams, but some men will find 5 milligrams enough. In some cases a 20 milligram dose is necessary. Tadalafil should be taken orally 30 minutes or longer before sexual activity.

Medical testing has shown that Tadalafil is effective in 60, of cases when used to treat erectile dysfunction in men. Most failure cases are from men that have had some form of surgery that made getting or maintaining an erection physically impossible.

Tadalafil produces results similar to viagra, but the effects of Tadalafil last longer than viagra. In addition, Tadalafil can be taken on an empty stomach or with a meal.

How Does Tadalafil Work

Medications like Tadalafil, Sildenafil, and levitra work by inhibiting a chemical called phosphodiesterase type 5. Because of their mode of action, these drugs are commonly referred to simply as PDE5 inhibitors.

When a man gets sexually excited, it triggers cells in the penis to produce nitric oxide. The increase in nitric oxide will in turn cause production of cyclic guanosine monophosphate (cGMP). The cGMP causes arteries in part of the penis to relax and allow more blood to flow through them. The increase in blood flow causes an erection.

If the enzyme phosphodiesterase type 5 (PDE5) is of sufficient quantity, it will attack the cGMP and erection will not be maintained. Tadalafil and other PDE5 inhibitors reduce the amount of PDE5 available to attack cGMP. With a reduction of PDE5, most men are able to maintain an erection to orgasm.

The recommended dose of Tadalafil is 10 mg before the planned sexual activity. For patients who received 10 mg dose of Tadalafil with no enough effect, we can recommend a dose of 20 mg. It should be taken 30 minutes-12 hours before sexual activity. The effectiveness of Tadalafil can last up to 24 (36) hours after the intake.

A wide range of opportunities that Tadalafil gives, allows men to enjoy a normal sexual life without the need to plan the period of effectiveness of the drug. Man, together with a partner has the opportunity to choose the right moment for intimacy within 36 hours.

The maximum recommended frequency of intakes is once a day. Tadalafil, however, is not advised to be taken every day as its daily long-term effect has not yet been studied.

Tadalafil not only improves the quality of erection, but also is able to restore spontaneity and efficiency of sexual relations in real life. Tadalafil is a reliable means of resuming sexual life for those who suffer from erectile dysfunction.