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Sildenafil Citrate, is a drug that is considered by many as being a wonder drug.
Sildenafil is an efficient anti-impotence medicine that was developed by Pfizer Company in 1998 and very soon received an approval of the FDA for the treatment of erectile dysfunction.
Sildenafil became the first pill ever to be approved at such a high level for the treatment of this sexual problem that had been overlooked before. This drug contains active ingredient that was named sildenafil citrate. Sildenafil is a patented name of the medicine, while the same active ingredient can appear in other drugs - for instance, Revatio, but also in generic pills that are sold over the Internet. Sildenafil comes as a blue diamond-shaped tablet for oral administration and there are three possible dosages - 25, 50 and 100 mg.
The way Sildenafil works
The discovery of sildenafil citrate - active ingredient of Sildenafil - revolutionized the methods of erectile dysfunction treatment. Before its appearance the only treatment available involved local injection into the tissues of the penis, which was quite painful. However, with the appearance of sildenafil citrate that could block certain enzymes responsible for blood outflow from the tissues of the penis, treating ED became a lot easier and faster. When the man gets aroused this information is processed in the brain and a signal is sent to the nerve cells in the penis. The nerve cells immediately start producing nitric oxide that stimulates the production of cyclic guanosine monophosphate (cGMP) by guanylate cyclase enzymes. The cGMP causes dilation of the arteries in the penis therefore allowing the blood to enter the corpora cavernosa of the penis. The main problem with erection is that there isn't enough cGMP produced to maintain a stable erection. Sildenafil works by blocking the production of PDE5 - a specific enzyme that decomposes cGMP not allowing it to build up and lead to a stable erection.
What is Sildenafil intended for?
The main objective of this wonder pill is a perfect solution to the problems of erectile dysfunction in men. It increases the ability to quickly achieve an erection and maintain it for a long time, thus increasing the prospects of success during sexual intercourse. The drug increases stamina, and helps achieving firm erection.
Sildenafil Side effects
Like all other medications, Sildenafil pills may also have some dangerous side effects. Side effects caused by taking Sildenafil vary from mild to moderate and usually disappear within a few hours:
- Headache
- Vomiting
- Abdominal pain
- Blurred vision
- Dizziness
Sildenafil Precautions
If you suffer from liver disorder or heart disease, the medication can lead to serious consequences. In such cases, you should inform your doctor about the history of your illness to choose a safe dose of Sildenafil right for you. In addition, people who are receiving treatment medications containing nitrates should avoid taking Sildenafil as it may drastically change the blood pressure.
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