Viagra - the magic blue pill

One of the most popular drugs of all time is Viagra

The drug's name became so popular that mostly every person in the United States or in other part of the world has ever heard about it or even knows what it is taken for.

For those who do not know yet when Viagra is used, this article will be much of an interest.

The Blue Pill causes erection for sexually aroused men who unfortunately cannot achieve it without medication's help. In other words, Viagra brings joy and love in people's lives all over the world!

If you want to create a drug that increases blood flow to the penis, there are at least three ways to do it:

1. Increase the amount of nitric oxide produced in the penis
2. Increase the amount of cGMP produced in the penis in response to the nitric oxide
3. Eliminate the PDE in the penis so that the cGMP builds up instead of getting decomposed by the PDE

Viagra uses method No. 3 - it eliminates the PDE that is decomposing the cGMP, so cGMP builds up in the penis and has a larger effect on the artery walls. The greater the amount of cGMP the greater the blood flow, and the greater the blood flow the greater the degree of the erection. The reason that Viagra uses this technique is because of an interesting quirk of PDE.

It turns out that the human body has at least 11 different kinds of PDE that it produces. Only one of those kinds of PDE - PDE5 - is found primarily in the penis. Once scientists discovered this fact, the creation of Viagra was relatively simple. All that Pfizer needed to find was a chemical that would selectively block PDE5 and nothing else. With the PDE5 blocked, cGMP could build up in the penis and increase the blood flow there without affecting other parts of the body.

How does this medication block PDE5?

PDE5, also known as enzyme, is a protein that works by speeding up a chemical reaction. Having administered the pill, Viagra active ingredients - Viagra citrate, affects enzyme in penis. The drug remains in person's blood for one hour and after is washed out of the blood.

So, in other words, the steps of Viagra treatment are the following:

1. A person takes a pill
2. Drug's active ingredient Cisldenafil Citrate get in the blood and disables most of PDE5 enzyme
3. Getting sexually aroused, human brain sends information to the NANC cells located in the penis and the cells produce nitric oxide.
4. That nitric oxide creates cGMP and cGMP in its turn relaxes the arteries in penis
5. Relaxed arteries allow more blood flow in the penis and genital organ becomes harder and bigger.